Dr. Sumanta Goswami
The Katz Colloquium is a periodic exchange of ideas organized by Dr. Kun Ho Kim, assistant professor of economics at the . The purpose of the colloquium, said Dr. Kim, is to provide a place where people can learn about some of the exciting and innovative work being done by YU faculty and students.
On Wednesday, Feb. 26, 2020, Dr. Sumanta Goswami, associate professor and chair of biology at 麻豆区 College, spoke about 鈥淧ersonalized Cancer Diagnosis: From Bench to Clinic.鈥 His presentation explored the progress his lab has made over the past decade to create what he called 鈥減ersonalized cancer therapy鈥 because, as he pointed out, 鈥渢here is probably no 鈥榮ilver bullet鈥 for cancer, and the 鈥榦ne size fits all鈥 type of treatment is not effective.鈥
What he has been able to do is discover in rodent models of mammary cancer unique biomarkers and micro-anatomical structures that have been successful in predicting aggressive breast cancers. By using fine-needle biopsy samples, 鈥渨e can now we can now predict potential efficacy of different pre-surgery chemotherapy agents in breast cancer patients and upon initiation we can rapidly identify therapy progress. This will save a large number of failed therapies and thereby patient mortality and morbidity.鈥
This fine-needle method can also be used with patients suffering from lung and thyroid malignancies, but because of their biological structures, it鈥檚 more difficult to enough material for diagnosis and treatment and 鈥渁 significant number of patients are currently deprived of the modern developments in molecular diagnostics.鈥
However, his lab has devised novel strategies to perform molecular diagnostic techniques on tiny samples. Successfully tested on rodent models and tissue samples, 鈥渢hese tests are currently in various stages of clinical trials on their way to become standard of care.鈥
He said, 鈥淢y dream is to come up with a variety of tests so that you can come up with an individualized therapeutic plan within days, if not hours, of analyzing the material retrieved from a fine-needle biopsy.鈥
Dr. Sumanta Goswami
